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Search Results for " ag 2 "

Targets Recommended: EGFR HER

31

抑制剂 & 化合物

302

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T4694	AG-1557 hydrochloride (189290-58-2(free base))	EGFR; HER	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	AG-1557 hydrochloride (189290-58-2(free base)) 是一种表皮生长因子受体 (EGFR) 酪氨酸激酶抑制剂 (pIC50: 8.194)。
T7493	AG-13958 AG-013958,N-[2-氟-5-[[3-[(1E)-2-(2-吡啶基)乙烯基]-1H-吲唑-6-基]氨基]苯基]-1,3-二甲基-1H-吡唑-5-甲酰胺	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	AG-13958 (AG-013958) 是 VEGFR 酪氨酸激酶抑制剂，可用于年龄相关性黄斑变性 (AMD) 的脉络膜新生血管形成的研究。
T6266	PP2 AGL 1879,AG 1879,AGL 1879	EGFR; Tyrosine Kinases; JAK; Src	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	PP2 (AG 1879,AGL 1879) 是 Lck/Fyn 抑制剂 (IC50:4/5 nM)，对 EGFR 的效力降低约 100 倍，对 ZAP-70、PKA 和 JAK2 无活性。
T1088	Repaglinide AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈	Potassium Channel; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Repaglinide (AG-EE 623ZW) 是一种能够用于2 型糖尿病的胰岛素促分泌剂。
T13238	Tyrphostin AG1433 SU1433,AG1433	VEGFR; PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	Tyrphostin AG1433 (AG1433) 是选择性的PDGFRβ和VEGFR-2 (Flk-1/KDR)抑制剂，IC50分别为 5.0 μM 和 9.3 μM。Tyrphostin AG1433有防止血管形成的活性。
T22253	AG-120 (racemic) 1-(4-氰基-2-吡啶基)-5-氧代-L-脯氨酰-2-(2-氯苯基)-N-(3,3-二氟环丁基)-N2-(5-氟-3-吡啶基)甘氨酰胺	Dehydrogenase	Metabolism
	AG-120 (racemic) 是 AG-120 的外消旋混合物，是一种可口服的异柠檬酸脱氢酶 1 型 (IDH1) 抑制剂，具有潜在的抗肿瘤活性。
T4052	KML29	Lipase	Metabolism
	KML29 是一种口服具有活性的、高度选择性的不可逆 MAGL 抑制剂，其对小鼠、大鼠和人的 IC50值分别为15 nM、43 nM 和 5.9 nM。它对 FAAH 在内的其他中心和外周丝氨酸水解酶的交叉反应极小。
T29372	2-Pyridineacetamide, 5-ethylthio- AG-41,AG 41,AG41
	2-Pyridineacetamide, 5-ethylthio- is a biochemical.
T29373	2-Pyridineacetamide, 5-methylthio- AG 42,AG-42 AG42
	2-Pyridineacetamide, 5-methylthio- is a biochemical.
T22456	Voreloxin hydrochloride SNS-595 hydrochloride,Vosaroxin,(3S-反式)-1,4-二氢-7-[3-甲氧基-4-(甲基氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸单盐酸盐	Apoptosis; Topoisomerase	Apoptosis; DNA Damage/DNA Repair
	Voreloxin hydrochloride (SNS-595 hydrochloride) 是一种新型拓扑异构酶 II 抑制剂，能够诱导 DNA 双链断裂，阻滞 G2 期，引起细胞凋亡。
T4554	AG 1406	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	AG 1406 是受体酪氨酸激酶 VEGF 受体 2 的选择性抑制剂。
T1452	Axitinib AG-013736,阿昔替尼,阿西替尼	VEGFR; PDGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Axitinib (AG-013736) 是一种多靶点酪氨酸激酶抑制剂，能够抑制 VEGFR1 (IC50:4 nM)，VEGFR2 (IC50:20 nM)，VEGFR3 (IC50:0.4 nM)，PDGFRβ (IC50:2 nM)。
T11724	JNJ-42226314	Lipase	Metabolism
	JNJ-42226314 是一种具有高选择性的非共价单酰基甘油脂肪酶 (MAGL) 抑制剂，具有抗伤害作用。JNJ-42226314 通过内源性大麻素-2-丙烯酰甘油（2-AG）在神经病理性疼痛和炎症性疼痛模型中显示出疗效。
T2346	Enasidenib 恩西地平,AG-221	Dehydrogenase; Isocitrate Dehydrogenase (IDH)	Metabolism
	Enasidenib (AG-221) 是口服具有活力的、可逆的、选择性IDH2突变酶抑制剂，抑制IDH2R140Q 和 IDH2R172K 的IC50分别为100 和 400 nM。
T14137	AG 1295	PDGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	AG 1295 是选择性血小板衍生生长因子受体酪氨酸激酶抑制剂。它能抑制 PDGFR 的自磷酸化，对 EGF 受体的自磷酸化无影响。
T4205	AG-494 Tyrphostin AG-494,AG 494,Tyrphostin B48	EGFR; CDK	Angiogenesis; Cell Cycle/Checkpoint; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	AG-494 (Tyrphostin B48) 是一种高效、选择性的 EGFR 酪氨酸激酶抑制剂，IC50为0.7 μM。它阻断 Cdk2 的激活并抑制 EGF 依赖的 DNA 合成。它抑制 EGFR、ErbB2、HER1-2 和 PDGF-R 的自磷酸化，IC50为 1.1、39、45 和 6 μM。
T3617	Ivosidenib 艾伏尼布,AG-120	Dehydrogenase; Isocitrate Dehydrogenase (IDH)	Metabolism
	Ivosidenib (AG-120) 是一种口服具有活力的异柠檬酸脱氢酶 1 的突变体酶 (mIDH1 enzyme) 抑制剂，能够使 d-2- hydroxyglutatrate (2-HG) 在体内降低。它具有良好的的安全性和临床活性，具有研究 AML 的潜力。
T4092	AG126 Tyrphostin AG126,AG 126	ERK; COX	Immunology/Inflammation; MAPK; Neuroscience
	AG126 (Tyrphostin AG126) 是一种酪氨酸激酶抑制剂，可阻止丝裂原活化蛋白激酶 p42MAPK(ERK2) 的激活。
T6554	JZL 184 JZL184	Lipase	Metabolism
	JZL 184 是不可逆的、选择性的MAGL 抑制剂，对MAGL 的选择性比 FAAH 高 300 倍以上。它可阻断脑膜中的 2-花生四烯酸甘油酯 (2-AG) 的水解 (IC50为 8 nM)。
T5815	MJN110 Cravatt Reagent	Lipase	Metabolism
	MJN110 (Cravatt Reagent) 是选择性的、口服具有活性的单酰基甘油脂肪酶 (MAGL) 抑制剂，对 hMAGL 和 2-花生四烯酸甘油酯 (2-AG) 的IC50分别为 9.1 nM 和 2.1 nM。它具有阿片类药物保护作用，具有显著的抗痛觉过敏活性。
T27811	LEI-106
	LEI-106, a novel potent sn-1 DAGLalpha inhibitor, blocks the hydrolysis of sn-1-oleoyl-2-AG, inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6.
T34521	SAR629 SAR 629,SAR-629
	SAR-629 is an MGL inhibitor or 2-AG degradation inhibitor.
T11070L	DO34	Others	Others
	DO34 is a highly potent and centrally active inhibitor of diacylglycerol lipase (IC50: 6 nM for DAGLα conversion of SAG to 2-AG).
T28235	OMDM169 OMDM 169,OMDM-169
	OMDM169 is a potent and selective MAGL inhibitor. OMDM169 could enhances 2-AG levels and of exerts analgesic activity via indirect activation of cannabinoid receptors. OMDM169 exhibited 0.13 microM<IC(50)<0.41 microM towards 2-AG hydrolysing activities in
T68451	AG-28262 besylate
	AG-28262 besylate is a VEGFR-2 Inhibitorwhich may affect alanine aminotransferase gene expression and enzymatic activity in the liver.
T38115	Fluprostenol serinol amide
	2-arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be metabolized by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to form PG 2-glyceryl esters. Fluprostenol serinol amide (Flu-SA) is a stable analog of PGF2α 2-glyceryl ester that has much greater stability. The biological activity of Flu-SA has not yet...
T37629	IDFP
	The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) hydrolyze 2-AG and AEA, respectively, thus terminating their biological function. IDFP is an organophosphorus compound that dually inhibits MAGL and F...
T35786	O-7460
	In humans, two forms of diacylglycerol lipase, DAGLα and DAGLβ, generate the endocannabinoid 2-arachidonoyl glycerol by attacking DAG at the sn-1 position. O-7460 is a selective inhibitor of 2-AG biosynthesis via DAGLα (IC50 = 690 nM). It demonstrates much weaker inhibition towards human monoacylglycerol lipase and rat brain fatty acid amide hydrolase (IC50s > 10 μM) and does not bind to CB1 or CB2 cannabinoid receptors (Kis > 10 μM). At 0-12 mg/kg, i.p. in mice, O-7460 was reported to dose-depe...
T37374	URB754
	URB754 is a potent and noncompetitive inhibitor of monoacylglycerol lipase (MAGL), exhibiting an IC50 value of 200 nM for the recombinant rat brain enzyme. However, it does not inhibit human recombinant, rat brain, or mouse brain MAGL at concentrations up to 100 μM. There is evidence that the MAGL inhibitory activity of URB754 may be attributed to the impurity bis(methylthio)mercurane (IC50 = 11.9 nM for rat recombinant MAGL) that is found in commercial preparations. URB754 inhibits rat brain fa...
T75834	Antagonist G TFA
	Antagonist G TFA 作为后叶加压素（vasopressin）的有效拮抗剂，同时对GRP和缓激肽具有弱拮抗作用。此外，Antagonist G 能够诱导AG-1转录，增强癌细胞对化疗的敏感性。
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...

化合物

AG-1557 hydrochloride (189290-58-2(free base))

Cat.No: T4694

Target: EGFR, HER

Cat.No: T7493

Synonym: AG-013958,N-[2-氟-5-[[3-[(1E)-2-(2-吡啶基)乙烯基]-1H-吲唑-6-基]氨基]苯基]-1,3-二甲基-1H-吡唑-5-甲酰胺

Target: VEGFR

Cat.No: T6266

Synonym: AGL 1879,AG 1879,AGL 1879

Target: EGFR, Tyrosine Kinases, JAK, Src

Cat.No: T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈

Target: Potassium Channel, PPAR

Tyrphostin AG1433

Cat.No: T13238

Synonym: SU1433,AG1433

Target: VEGFR, PDGFR

AG-120 (racemic)

Cat.No: T22253

Synonym: 1-(4-氰基-2-吡啶基)-5-氧代-L-脯氨酰-2-(2-氯苯基)-N-(3,3-二氟环丁基)-N2-(5-氟-3-吡啶基)甘氨酰胺

Target: Dehydrogenase

Cat.No: T4052

Target: Lipase

2-Pyridineacetamide, 5-ethylthio-

Cat.No: T29372

Synonym: AG-41,AG 41,AG41

2-Pyridineacetamide, 5-methylthio-

Cat.No: T29373

Synonym: AG 42,AG-42 AG42

Voreloxin hydrochloride

Cat.No: T22456

Synonym: SNS-595 hydrochloride,Vosaroxin,(3S-反式)-1,4-二氢-7-[3-甲氧基-4-(甲基氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸单盐酸盐

Target: Apoptosis, Topoisomerase

Cat.No: T4554

Target: VEGFR

Cat.No: T1452

Synonym: AG-013736,阿昔替尼,阿西替尼

Target: VEGFR, PDGFR, c-Kit

Cat.No: T11724

Target: Lipase

Cat.No: T2346

Synonym: 恩西地平,AG-221

Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)

Cat.No: T14137

Target: PDGFR

Cat.No: T4205

Synonym: Tyrphostin AG-494,AG 494,Tyrphostin B48

Target: EGFR, CDK

Cat.No: T3617

Synonym: 艾伏尼布,AG-120

Target: Dehydrogenase, Isocitrate Dehydrogenase (IDH)

Cat.No: T4092

Synonym: Tyrphostin AG126,AG 126

Target: ERK, COX

Cat.No: T6554

Synonym: JZL184

Target: Lipase

Cat.No: T5815

Synonym: Cravatt Reagent

Target: Lipase

Cat.No: T27811

Cat.No: T34521

Synonym: SAR 629,SAR-629

Cat.No: T11070L

Target: Others

Cat.No: T28235

Synonym: OMDM 169,OMDM-169

AG-28262 besylate

Cat.No: T68451

Fluprostenol serinol amide

Cat.No: T38115

Cat.No: T37629

Cat.No: T35786

Cat.No: T37374

Antagonist G TFA

Cat.No: T75834

Cat.No: T70882

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00056	AG-2 Protein, Human, Recombinant (His) HPC8,AG2,AG-2,hAG	Human	HEK293 Cells
	Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of E...
TMPK-00698	AGR2 Protein, Mouse, Recombinant (His) AG2,HPC8,hAG-2,Anterior ...	Mouse	E. coli
	Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression.
TMPJ-01319	TINAGL1 Protein, Human, Recombinant (His) LCN7,Tubulointerstitial nephritis antigen-like (TINAG	Human	HEK293 Cells
	TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells.
TMPH-01478	HIST1H2AG Protein, Human, Recombinant (His)	Human	E. coli
	HIST1H2AG Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-00536	Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)	EBV	P. pastoris (Yeast)
	Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-ass...
TMPJ-00050	AG-3 Protein, Human, Recombinant (His) BCMP11,hAG-3,AG-3,AG3,Anterior Gr...	Human	HEK293 Cells
	Anterior Gradient Protein 2(AG-2) and Anterior Gradient Protein 3 (AG-3) are human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan (hAG-3 protein). AG-3 could serve as a prognostic marker for survival in patients with low grade and high grade serous ovarian carcinomas.
TMPY-03400	DCBLD1 Protein, Human, Recombinant (His) dJ94G16.1,discoidin, CUB and LCCL domain containing 1,RP1-94...	Human	HEK293 Cells
	Discoidin, also known as DCBLD1, contains 1 CUB domain, 1 F5/8 type C domain and 1 LCCL domain. It is a 715 amino acid single-pass membrane protein. Discoidin has a discoidin I-like domain which shares a common C-terminal region of about 110 amino acids with the FA58C domain, but whose N-terminal 40 amino acids are much less conserved. Discoidin gene contains 31 distinct gt-ag introns. Transcription produces 18 different mRNAs, 16 alternatively spliced variants and 2 unspliced forms. Discoidin i...
TMPH-01298	EPHX1 Protein, Human, Recombinant (His)	Human	E. coli
	Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Plays a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Metabolizes the abundant endocannabinoid 2-arachidonoylglycerol (2-AG) to free arachidonic acid (AA) and glycerol.
TMPJ-01028	Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag) Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,Cl...	Human	HEK293 Cells
	Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat...
TMPY-02921	CDK2AP2 Protein, Human, Recombinant (His) DOC-1R,p14,cyclin-dependent kinase 2 associated pro...	Human	E. coli
	CDK2AP2 belongs to the CDK2AP family. Members of this family of proteins are cell-growth suppressors, associating with and influencing the biological activities of important cell cycle regulators in the S phase including monomeric non-phosphorylated cyclin-dependent kinase 2 (CDK2) and DNA polymerase alpha/primase. CDK2AP2 contains 5 distinct gt-ag introns. Transcription produces 7 different mRNAs, 6 alternatively spliced variants and 1 unspliced form. There are 2 non overlapping alternative las...
TMPY-01442	DMBT1 Protein, Human, Recombinant (His) GP340,deleted in malignant brain tumors 1,muclin	Human	HEK293 Cells
	Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Protein T1,suppression of tumorigenicity 2,Ly84,DER...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02011	CD96 Protein, Human, Recombinant (His) CD96 molecule,TACTILE	Human	HEK293 Cells
	CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His) Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His) A630052E07Rik,OSF-2,Osf2,PLF,AI74...	Mouse	HEK293 Cells
	Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPY-01717	VEGF164 Protein, Mouse, Recombinant vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子	Mouse	Baculovirus Insect Cells
	VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-02096	TACI Protein, Human, Recombinant (His) RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-06056	KRAS Protein, Human, Recombinant (G12D, His) KRAS1,K-RAS4B,Kirsten rat sarcoma viral oncogene homolog,RAL...	Human	E. coli
	KRAS Protein, Human, Recombinant (G12D, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22 kDa and the accession number is P01116-2.
TMPY-00751	TrkB Protein, Human, Recombinant (His) trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His) SGP-2,AAG4,KUB1,CLI,CLU2,TRPM...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His) BTN3.1,butyrophilin subfamily 3 member A1,BTF5,BT3.1,CD2...	Human	HEK293 Cells
	BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149) PLGF,PGFL,placental growth factor,D12S1900,SHGC-107...	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a) SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1	Human	E. coli
	SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-01935	c-Kit Protein, Human, Recombinant (His) PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncog...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-04356	GSK3B Protein, Human, Recombinant (His) glycogen synthase kinase 3 beta,glycogen synthase kinase 3 β	Human	Baculovirus Insect Cells
	GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02500	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) Gp39,AW208766,Brp39,chitinase 3 like 1	Mouse	HEK293 Cells
	YKL-40/CHI3L1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.3 kDa and the accession number is Q61362-2.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST) v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an...
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated FCGR2,FCGR21,CD32A,FCG2,...	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04644	PDGFB Protein, Human, Recombinant (His) platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...	Human	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted...
TMPY-05414	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) D6H12S2489E,NKG2-D,killer cell le...	Mouse	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-01709	HIF-1 alpha Protein, Human, Recombinant (His) bHLHe78,HIF-1 α,hypoxia inducible factor 1, alpha subunit (b...	Human	E. coli
	HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has...
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) interleukin 5 receptor, alpha,IL5R,CD125,CDw12<...	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His) KRAS2,C-K-RAS,Kirsten rat sarcoma viral oncogene ho...	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His) IL1RL1,IL‑1 R4,DER4,ST2,IL33R,interleukin 1 recepto...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00747	Nectin-2 Protein, Human, Recombinant (His) PVRR2,Nectin-2,poliovirus receptor-related...	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-05427	CD19 Protein, Human, Recombinant (hFc) CVID3,B4,CD19 molecule	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,Transforming growt...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-04051	c-Kit Protein, Human, Recombinant (hFc) SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene h...	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293) HSCR3,ATF2,HFB1-GDNF,ATF1,glial cell derived neurot...	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-00005	FGF-8a Protein, Human, Recombinant fibroblast growth factor 8 (androgen-induced),FGF-8,AIGF,NEW...	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-03425	Tau Protein, Human, Recombinant (His) PPND,FTDP-17,MTBT1,DDPAC,MAPTL,MTBT2,microtubule-as...	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP...
TMPY-01199	CD74 Protein, Human, Recombinant (His) II,DHLAG,Ia-GAMMA,CD74 molecule, major histocompati...	Human	HEK293 Cells
	CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated TMIGD2,IGPR-1,transmembrane and immunoglobulin doma...	Human	HEK293 Cells
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent in mouse and rat genomes. The immunoglobulin domain of IGPR-1 was predicted to be Ig V (variable) fold and was found to be highly similar to the Ig domain of myelin-associated glycoprotein.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy. CD28H/TMIGD2 Protein, Hu...
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) ST2V,FIT-1,DER4,interleukin 1 receptor-like 1,T1,IL...	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc) HML2,CD301,CLECSF13,HML,MGL,C-type lectin domain fa...	Human	HEK293 Cells
	CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPY-02432	VEGF164 Protein, Rat, Recombinant 血管内皮生长因子,vascular endothelial growth factor A	Rat	Baculovirus Insect Cells
	VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His) trk-B,neurotrophic tyrosine kinase, receptor, type 2	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) neuropilin 1,NRP,VEGF165R,BDCA4,Neuropilin-1,NP1,CD304	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
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重组蛋白

AG-2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00056

Species: Human

Expression System: HEK293 Cells

AGR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00698

Species: Mouse

Expression System: E. coli

TINAGL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01319

Species: Human

Expression System: HEK293 Cells

HIST1H2AG Protein, Human, Recombinant (His)

Cat.No: TMPH-01478

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)

Cat.No: TMPH-00536

Species: EBV

Expression System: P. pastoris (Yeast)

AG-3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00050

Species: Human

Expression System: HEK293 Cells

DCBLD1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03400

Species: Human

Expression System: HEK293 Cells

EPHX1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01298

Species: Human

Expression System: E. coli

Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)

Cat.No: TMPJ-01028

Species: Human

Expression System: HEK293 Cells

CDK2AP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02921

Species: Human

Expression System: E. coli

DMBT1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01442

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Cat.No: TMPJ-00850

Species: Mouse

Expression System: HEK293 Cells

Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

Cat.No: TMPY-00891

Species: Human

Expression System: HEK293 Cells

CD96 Protein, Human, Recombinant (His)

Cat.No: TMPY-02011

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Cat.No: TMPY-04113

Species: Human

Expression System: E. coli

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01613

Species: Mouse

Expression System: HEK293 Cells

VEGF164 Protein, Mouse, Recombinant

Cat.No: TMPY-01717

Species: Mouse

Expression System: Baculovirus Insect Cells

TACI Protein, Human, Recombinant (His)

Cat.No: TMPY-02096

Species: Human

Expression System: HEK293 Cells

FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

Cat.No: TMPY-00341

Species: Human

Expression System: HEK293 Cells

KRAS Protein, Human, Recombinant (G12D, His)

Cat.No: TMPY-06056

Species: Human

Expression System: E. coli

TrkB Protein, Human, Recombinant (His)

Cat.No: TMPY-00751

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (CLU34, His)

Cat.No: TMPY-01691

Species: Human

Expression System: HEK293 Cells

BTN3A1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04844

Species: Human

Expression System: HEK293 Cells

PLGF/PGF Protein, Human, Recombinant (aa 19-149)

Cat.No: TMPY-05288

Species: Human

Expression System: E. coli

SDF-1 Protein, Human, Recombinant (isoform a)

Cat.No: TMPY-02820

Species: Human

Expression System: E. coli

c-Kit Protein, Human, Recombinant (His)

Cat.No: TMPY-01935

Species: Human

Expression System: HEK293 Cells

GSK3B Protein, Human, Recombinant (His)

Cat.No: TMPY-04356

Species: Human

Expression System: Baculovirus Insect Cells

YKL-40/CHI3L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02500

Species: Mouse

Expression System: HEK293 Cells

C-ABL/ABL1 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04396

Species: Human

Expression System: Baculovirus Insect Cells

CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-01985

Species: Human

Expression System: HEK293 Cells

PDGFB Protein, Human, Recombinant (His)

Cat.No: TMPY-04644

Species: Human

Expression System: P. pastoris (Yeast)

NKG2D/CD314 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-05414

Species: Mouse

Expression System: Baculovirus Insect Cells

HIF-1 alpha Protein, Human, Recombinant (His)

Cat.No: TMPY-01709

Species: Human

Expression System: E. coli

IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)

Cat.No: TMPY-01871

Species: Human

Expression System: HEK293 Cells

KRAS Protein,Human, Recombinant (Q61H, His)

Cat.No: TMPY-01888

Species: Human

Expression System: E. coli

ST2/IL-1 RL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01359

Species: Human

Expression System: HEK293 Cells

Nectin-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00747

Species: Human

Expression System: HEK293 Cells

CD19 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05427

Species: Human

Expression System: HEK293 Cells

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

c-Kit Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04051

Species: Human

Expression System: HEK293 Cells

GDNF Protein, Human, Recombinant (HEK293)

Cat.No: TMPY-02792

Species: Human

Expression System: HEK293 Cells

FGF-8a Protein, Human, Recombinant

Cat.No: TMPY-00005

Species: Human

Expression System: E. coli

Tau Protein, Human, Recombinant (His)

Cat.No: TMPY-03425

Species: Human

Expression System: E. coli

CD74 Protein, Human, Recombinant (His)

Cat.No: TMPY-01199

Species: Human

Expression System: HEK293 Cells

CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-05586

Species: Human

Expression System: HEK293 Cells

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00849

Species: Human

Expression System: HEK293 Cells

CLEC10A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02971

Species: Human

Expression System: HEK293 Cells

VEGF164 Protein, Rat, Recombinant

Cat.No: TMPY-02432

Species: Rat

Expression System: Baculovirus Insect Cells

TrkB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02231

Species: Mouse

Expression System: HEK293 Cells

Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

Cat.No: TMPY-02367

Species: Human

Expression System: HEK293 Cells

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